Instinct Bio Technical Company Holdings Inc. (Nasdaq: BIOT) announced a strategic collaboration with Invitrx Therapeutics, Inc. (INVITRX) through a Memorandum of Agreement (MOA) signed by its subsidiaries. The partnership outlines two key workstreams: manufacturing and selling GENREVER cosmetic products in the United States and supplying concentrated exosomes and conditioned media for clinics and an in-hospital cell processing center in Indonesia.
The collaboration builds on a six-year commercial relationship where Instinct Bio sourced raw materials from INVITRX for its quality assurance processes. Under the proposed agreement, Instinct Bio will license the GENREVER trademark, while Artisans Production Co., Ltd. contributes proprietary formulations and raw materials. INVITRX is expected to manufacture GENREVER products at its U.S. GMP facility, positioning the brand as a premium Japanese cosmetics line in the U.S. market, subject to regulatory approvals.
In Indonesia, the parties plan to collaborate on establishing a regenerative medicine platform. INVITRX would supply concentrated exosomes and conditioned media for proposed clinics and an in-hospital cell processing center, supporting one of Asia's fastest-growing healthcare markets. The companies will negotiate definitive commercial agreements covering manufacturing, supply, and commercialization while progressing regulatory assessments.
Tomoki Nagano, CEO of Instinct Bio, stated: "This collaboration represents an important step in our strategy to expand Instinct Bio's international platform. By bringing together the GENREVER brand, Artisans Production's proprietary formulations and INVITRX's U.S. GMP manufacturing capabilities, we believe we are creating a strong foundation for future growth in both the United States and Southeast Asia."
The initiative highlights Instinct Bio's commitment to regenerative medicine and longevity technologies. For more information, visit https://instinct-biot.com/. INVITRX operates a U.S. GMP manufacturing facility and develops cell-derived biological materials.
Forward-looking statements in the release caution that the MOA establishes a framework for negotiation, and there is no assurance definitive agreements will be reached or the collaboration completed. Risks include regulatory approvals, manufacturing challenges, and market acceptance.


